Project Title: Vitamin D metabolizing enzymes in triple negative breast cancer

Faculty Sponsor: Jessica Kelts

Department: Chemistry and Biochemistry

Telephone: 810.762.3218

E-Mail: jkelts@umflint.edu

Project Description: Examining the changes in vitmain D metabolizing enzyme mRNA by RT-PCR and protein by Western blot in various triple negative breast cancer cells.

Student Tasks & Responsibilities: Students will be responsible for running western blots and RT-PCR experiments.  Some students may be responsible for maintaining mammalian cell lines.  Students will have to submit progress reports every other week and will expected to complete a summary paper at the end of each semester.

Minimum Student Qualifications: Students must be biochemistry majors that have completed CHM 450 and CHM 451 to work on this project.  They must also complete a CHM 299 paper on the background of this project and complete CHM 499 with me or another chemistry professor before doing research on this project through UROP.

Proposed Starting Date: 01/01/2013

Proposed Ending Date: 05/01/2014